of Biological Regulation, Weizmann Institute of Science, Rehovot 7610001, Israel. 3Department of Computer Science and Applied Mathematics and Department of Biological Regulation, Weizmann Institute, Rehovot, Israel. Carlos Caldas, 234 Herzl Street, POB 26, Rehovot 7610001 Israel, Comprehensive list of centers and institutes, Faculty of Mathematics and Computer Science, Swiss Society Institute for Cancer Prevention Research, EKARD Institute for Cancer Diagnosis Research, Dwek Institute for Cancer Therapy Research, de Picciotto Cancer Cell Observatory in Memory of Wolfgang and Ruth Lesser, The Nancy and Stephen Grand Israel National Center for Personalized Medicine (G-INCPM), de Botton Institute for Protein Profiling, David and Fela Shapell Family Institute for Preclinical Studies, The Dana and Yossie Hollander Center for Structural Proteomics. Bacteria in nature reside in organized communities, termed biofilms, which are composed of multiple individual cells adhering to … The role of epithelial MHCII in maintaining tissue homeostasis and in tissue pathologies such as IBD and cancer. Amir Bahat 1 and ; Atan Gross 2; Department of Biological Regulation, Weizmann Institute of Science, Rehovot 7610001, Israel ↵ 2 To whom correspondence should be addressed: Dept. Clore Garden of Science. Chaim Weizmann lab. 2 Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, John Vane … This is achieved by … Affiliations 1 Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel. The lab of host-pathogen genomics is interested in how individual encounters between host and pathogenic bacteria can ultimately define the outcome of infection. Weizmann institute - Biological Regulation. 11 Department of … A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. The Department of Biological Regulation is comprised of approximately 170 people organized in 14 research groups. Renal function through sodium grandients; Non-invasive, high resolution sodium MRI. Department of Neurobiology. Department of Immunology. 9 Department of Immunology, Weizmann Institute of Science, Rehovot, Israel. Department of Veterinary Resources. Shapell Holocaust Memorial Plaza. Using a powerful combination of cutting-edge single cell genetic and genomic approaches, we wish to address what forms the basis for successful immune clearance, from the level of individual infected cells to that of the whole organism, and why, in some cases, sterilization is incomplete? These include biochemical, molecular and physiological methods, organ and tissue cultures, and whole animal studies utilizing mice and fish. Affiliations 1 Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel. Department of Biological Regulation Weizmann UK Building for Biocomplexity Research, room 014 Weizmann Institute of Science 234 Herzl St. Rehovot, 76100. Functions and modes of action of long RNAs, Functions of long noncoding RNAs in establishing cell identify, Chromatin modifiers in neurological disease, Combination of kinase inhibitors and monoclonal antibodies for cancer therapy, Molecular bases of tumor progression and roles for growth factors, Eytan Ruppin Hyperpolarized magnetic resonance spectroscopy and imaging of cancer metabolism; searching for novel metabolic markers of cancer. : 972-8-9343656; Fax: 972-8-9344116; E-mail: atan.gross{at}weizmann… 2 Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, 84105 Beer-Sheva, Israel. Genome and epigenome regulation - Prof. Amos Tanay Clore Garden of Science. Growth factors and their receptors in cancer - Prof. Yossi Yarden, Investigating functional, metabolic and architectural features of normal and malignant tissues with magnetic resonance techniques - Prof. Hadassa Degani The roles of gonadotropins and EGF-like factors in triggering ovulation. We are located in the Candiotty and Britannia buildings, which … Chaim Weizmann lab. Vascularization during pregnancy and cancer development - Prof. Michal Neeman Contact Information. 3Center for Bioinformatics and Computational Biology, University of Maryland Institute for … NMR, EPR, smFRET, cryoEM, CLEM, optical microscopy, correlative imaging methods, advanced mammalian cell models. 7Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel. A diversity of methodologies and experimental approaches are being used in order to tackle these pivotal issues in biology. (2)Department of Biological Regulation, Weizmann Institute of Science, Rehovot 7610001, Israel ayelet.erez@weizmann.ac.il. 2 1] Department of Biological Regulation, Weizmann Institute of Science, Rehovot … Department of Neurobiology. The control of reproduction - Prof. Nava Dekel 10 Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel. Since de-regulation of biological control circuits often underlays human diseases (e.g., malignant transformation, stroke, infertility, and defective tissue regeneration after injury), we make many efforts to implement the results of our studies in research projects leading to the development of new tools for early diagnosis, along with novel compounds suitable for pharmacological interventions. Together with the Faculty of Biochemistry, research efforts span the understanding of life at all levels, from the … Ovulation as a tissue remodeling process. Protein degradation by the ubiquitin/proteasome system - Prof. Ami Navon 4Department of Surgical Oncology, … A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. In addition, some researchers of the Department are using methodologies and concepts of systems biology, host-pathogen interactions and a variety of imaging methods, including magnetic resonance imaging (MRI). Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the ongoing coronavirus disease 19 (COVID-19) pandemic. 9Israel National … We are located in the Candiotty and Britannia buildings, which are equipped with all the cutting-edge facilities required for running excellent research endeavors. Understanding the role of epithelial cells in shaping the landscape of mucosal adaptive immunity. Regulation of the meiotic cell cycle: use of rodent oocytes as a model system. Electronic address: ilana.kolodkin-gal@weizmann.ac.il. Overview The Department of Biological Regulation is comprised of approximately 170 people organized in 13 research groups. Tel. A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Search for more papers by this author. (4)Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel. ... Weizmann Car Pavilion. The Department of Biological Regulation is comprised of approximately 170 people organized in 13 research groups. We are located in the Candiotty and Britannia buildings, which are equipped with all the cutting-edge facilities required for running excellent research endeavors. Department of Biological Regulation. (5)Department of Biological Services, Weizmann Institute of Science, Rehovot 76100, … My main research interest is developing novel techniques for biomedical image analysis. Shapell Holocaust Memorial Plaza. Department of Biological Regulation. Department of Molecular Cell Biology. Short Biography. We are located in the Candiotty and Britannia buildings, which … Our research is concentrated on the regulation of processes responsible for the concerted action of cells, tissues, and organs. 234 Herzl Street, POB 26, Rehovot 7610001 Israel. A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. The Department of Biological Regulation is comprised of approximately 160 people organized in 13 research groups. 3 … Department of Molecular Cell Biology. A diversity of methodologies and experimental approaches are being used in order to tackle these pivotal issues in biology. This is achieved by applying cross-disciplinary single-cell analysis platforms that collectively enable us to extensively profile and precisely monitor host-pathogen interactions within the context of in vivo infections. Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel. Organizer: Department of Biological Regulation Contact: tamar.cohen@weizmann.ac.il Add the event UVB-Induced Tumor Heterogeneity Directs Immune Response in Melanoma to the calendar The work in the lab centers on salmonella infection of mouse macrophages as a tractable in vitro host-pathogen system. 8Department of Immunology, Weizmann Institute of Science, Rehovot, Israel. Nitric oxide (NO) is a signaling molecule that … 3 Life Sciences Core Facilities, Weizmann … I received my PhD in applied mathematics and computer science from Weizmann … These include biochemical, molecular and physiological methods, organ and tissue cultures, and whole animal studies utilizing mice and fish. How do changes in mitochondria function effect the initiation/progression of Fibromyalgia? The lab of host-pathogen genomics is interested in how individual encounters between host and pathogenic bacteria can ultimately define the outcome of infection. Department of Biological Regulation. Chaim and Vera Weizmann … Departments of ‡ Biological Regulation, ** Veterinary Resources, and §§ Immunology, The Weizmann Institute of Science, Rehovot 76100, Israel, the ¶ Department of Neurobiochemistry, … The main projects that are currently performed in the department are: Host-pathogen interactions - Dr. Roi Avraham Epigenetics in stem cells and cancer: developing and applying single-molecule imaging technologies to study the epigenetic code - Dr. Efrat Shema Dr. Moshe Biton. Tel: +972-8-934-4937 Email Department of Immunology. The development and demise of ovarian follicles in vivo and in vitro: the role of apoptosis. Aaron Ciechanover We use this model to develop state of the art high throughput genomic tools and interdisciplinary approaches, and then apply them to various in vivo infection models to address critical biological aspects of host-pathogen biology. We are located in the Candiotty and Britannia … 1 Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel. ECM remodeling: from biophysical principles to drug design - Prof. Irit Sagi Department of Veterinary Resources. Piven. Chaim and Vera Weizmann … Molecular regulation of ovulatory changes in mammals. (2)Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel. Weizmann Institute of Science Rehovot 76100, ISRAEL Weizmann UK Building for Biocomplexity Research Room 17. Cell-to-cell communication: regulation of expression, posttranslational modification, degradation and function of the gap junction proteins, Cx43 and Cx37. Cellular regulation of CPEB4 liquid-liquid phase separation. Overview The Department of Biological Regulation is comprised of approximately 170 people organized in 14 research groups. Intracellular signaling cascades in health and disease - Prof. Rony Seger The main projects that are currently performed in the department are: Host-pathogen interactions - Dr. Roi Avraham, Cell metabolism in health and disease - Dr. Ayelet Erez, Protein degradation by the ubiquitin/proteasome system - Prof. Ami Navon, Vascularization during pregnancy and cancer development - Prof. Michal Neeman, ECM remodeling: from biophysical principles to drug design - Prof. Irit Sagi, Intracellular signaling cascades in health and disease - Prof. Rony Seger, Epigenetics in stem cells and cancer: developing and applying single-molecule imaging technologies to study the epigenetic code - Dr. Efrat Shema, Epigenetics in development and disease - Prof. Amos Tanay, Cellular functions of long noncoding RNAs - Dr. Igor Ulitsky, The development of the vascular system - Dr. Karina Yaniv, Growth factors and their receptors in cancer - Prof. Yossi Yarden, Cellular structural biology of human amyloid proteins - Prof. Philipp Selenko, Investigating functional, metabolic and architectural features of normal and malignant tissues with magnetic resonance techniques - Prof. Hadassa Degani, The meiotic cell cycle, angiogenic events associated with follicle development and embryo plantation - Prof. Nava Dekel, Investigating ovarian follicle physiology, regulation and demise in mammals with emphasis on the ovulatory response, including the control of oocyte maturation, transformation of the follicle into corpus luteum and culminating with the release of the fertilizable ovum - Prof. Alex Tsafriri. The resumption of meiosis and its regulation. ... Weizmann Car Pavilion. Avigdor Scherz and Yoram Salomon of the Department of Plant and Environmental Sciences and the Department of Biological Regulation, respectively, at the Weizmann Institute … PMID: 30082427 PMCID: PMC6124554 DOI: 10.1242/dmm.033332 Abstract Nitric oxide (NO) is a signaling molecule that plays important roles in diverse biological … Exploring novel cell-cell interactions in food allergies, IBD and cancer. Electronic address: igor.ulitsky@weizmann.ac.il. Mechanisms involved in successful implantation. Establishing the role of mitochondrial carrier homolog 2 (MTCH2) in regulating the shape of mitochondria, metabolism and apoptosis, Develop inhibitors for MTCH2 as potential therapies of diseases such as acute myeloid leukemia (AML) and obesity, Vascular remodelling in reproduction and development, Protocols, Reporter genes and Probes for molecular imaging, The nuclear translocation of signaling protein as a drug target for cancer and inflammation, Develop peptide inhibitors of the nuclear translocation of ERK/JNK/p38 for the cure of cancer and inflammation, Development of small molecular weight inhibitors of the nuclear translocation of ERK for the cure of cancer, The mechanisms and roles of MEK nuclear translocation, ERK1c in the regulation of Golgi fragmentation, The mechanisms of golgi translocation of ERK1c, Mechanism of ERK1c-regulated Golgi architecture, Neuronal alpha-synuclein aggregation in Parkinson's disease, Structural Biology, Cell Biology, Neurobiology, Biophysics. Maicol Mancini 1, Hilah Gal … 1 Department of Biological Regulation, Weizmann Institute of Science, 7610001 Rehovot, Israel. Find researchers and browse publications, full-texts, contact details and general information related to the Department of Biological Regulation at Weizmann Institute of Science Advanced methods for analysis of dynamic contrast enhanced MRI based on a combined model free and model based method. Estrogen regulation of angiogenesis and perfusion of breast cancer; from molecular mechanisms to functional MRI of the microvascular physiology, Molecular characterization of the ovulatory cascade. Since de-regulation of biological control circuits often underlies human diseases (e.g., malignant transformation, stroke, infertility, and defective tissue regeneration after injury), we make many efforts to implement the results of our studies in research projects leading to the development of new tools for early diagnosis, along with novel compounds suitable for pharmacological interventions. Author Information. Perfusion and angiogensis in lung cancer: The role of the bronchial and pulmonary vascular network using Fluorescence and magnetic resonance imaging methods, Molecular magnetic resonance imaging of the estrogen receptor, Synthesis of new, high affinity ligands of the estrogen receptor as probes for molecular imaging, Structuaral studies (x-ray crystalography and NMR) of the estrogen receptor - targeted ligands complex, Functional activities and molecular imaging of the new targeted ligands in estrogen receptor positive huaman breast cancer cells, Mechanisms of lymphatic metastasis in breast cancer; In vivo fluorescence and magnetic resonanc imaging, Advanced non invasive MRI methods for breast cancer detection and diagnosis ; clinical investigations, 3D Tracking of the mammary tree using diffusion tensor magnetic resonance imaging. T helper cells' role in maintaining tissue homeostasis. Our research is concentrated on the regulation of processes responsible for the concerted action of cells, tissues, and organs. Department of Molecular Cell Biology. 2Department of Biological Regulation, Weizmann Institute of Science, 7610001 Rehovot, Israel. Cellular functions of long noncoding RNAs - Dr. Igor Ulitsky Using comprehensive, quantitative, unbiased tools to analyse the molecular interactions that underlie distinct host-pathogen subpopulations and their impact on disease outcome. In addition, some researchers of the Department are using methodologies and concepts of systems biology, host-pathogen interactions and a variety of imaging methods, including magnetic resonance imaging (MRI). Department of Neurobiology. Active enhancers in mammals … Cell death and metabolism - Prof. Atan Gross Department of Veterinary Resources. 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